Search on: ONCOGENE PROTEINS, E7 
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Descriptor English:   Papillomavirus E7 Proteins 
Descriptor Spanish:   proteínas E7 del papilomavirus 
Descriptor Portuguese:   Proteínas E7 de Papillomavirus 
Synonyms English:   E7 Oncogene Proteins
E7 Proteins, Papillomavirus
Oncogene Protein E7, Papillomavirus
Oncogene Proteins, E7  
Tree Number:   D12.776.624.664.520.420
Definition English:   ONCOGENE PROTEINS from papillomavirus that deregulate the CELL CYCLE of infected cells and lead to NEOPLASTIC CELL TRANSFORMATION. Papillomavirus E7 proteins have been shown to interact with various regulators of the cell cycle including RETINOBLASTOMA PROTEIN and certain cyclin-dependent kinase inhibitors. 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   51159 
Unique Identifier:   D050725 

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